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Let 
, ..., 
 be Real Integrable Functions over
the Closed Interval 
, then the Determinant of their integrals 
satisfies
See also Gram-Schmidt Orthonormalization
References
Gradshteyn, I. S. and Ryzhik, I. M.  Tables of Integrals, Series, and Products, 5th ed.  San Diego, CA:
  Academic Press, p. 1100, 1979.