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The summary function
Mertens function obeys
Lehman (1960)  gives an algorithm for computing 
 with 
 operations,
while the Lagarias-Odlyzko (1987) algorithm for computing the Prime Counting Function 
 can be modified
to give 
 in 
 operations.
See also Mertens Conjecture, Möbius Function
References
Lagarias, J. and Odlyzko, A.  ``Computing  
Lehman, R. S.  ``On Liouville's Function.''  Math. Comput. 14, 311-320, 1960.
 
Odlyzko, A. M. and te Riele, H. J. J.  ``Disproof of the Mertens Conjecture.''  J. reine angew. Math. 357, 138-160, 1985.
 
Sloane, N. J. A.  Sequences
A028442 and
A002321/M0102
in ``An On-Line Version of the Encyclopedia of Integer Sequences.''
http://www.research.att.com/~njas/sequences/eisonline.html and Sloane, N. J. A. and Plouffe, S.
The Encyclopedia of Integer Sequences.  San Diego: Academic Press, 1995.
 
: An Analytic Method.'' J. Algorithms 8, 173-191, 1987.